Deciphering the assembly process of PQQ dependent methanol dehydrogenase

Abstract Pyrroloquinoline quinone (PQQ)-dependent methanol dehydrogenases (MDHs), the periplasmic metalloenzymes in Gram-negative methylotrophic bacteria, play a pivotal role in methane and methanol bio-utilization. Although the structures of many PQQ-dependent MDHs have been resolved, including the...

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Bibliographic Details
Published in:Nature Communications
Main Authors: Haichuan Zhou, Junqing Sun, Jian Cheng, Min Wu, Jie Bai, Qian Li, Jie Shen, Manman Han, Chen Yang, Liangpo Li, Yuwan Liu, Qichen Cao, Weidong Liu, Haixia Xiao, Hongjun Dong, Feng Gao, Huifeng Jiang
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Online Access:https://doi.org/10.1038/s41467-025-61958-w