Temporal and spatial pattern of DNA damage in neurons following spinal cord Injury in mice

Abstract Background Deficient DNA repair and excessive DNA damage contribute to neurodegenerative disease. However, the role of DNA damage and repair in spinal cord injury (SCI) is unclear. SCI, a debilitating disruption of the structural and biological network of the spinal cord, is characterized b...

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書誌詳細

出版年:	Journal of Biomedical Science
主要な著者:	Elle EM Scheijen, Naomi Veeningen, Sam Duwé, Anna Ivanova, Jana Van Broeckhoven, Sven Hendrix, David M Wilson
フォーマット:	論文
言語:	英語
出版事項:	BMC 2025-01-01
主題:	Spinal cord injury DNA damage Oxidative stress Gamma-H2AX Neuronal death DNA repair
オンライン･アクセス:	https://doi.org/10.1186/s12929-024-01104-8