CD44 mediates the internalization of foot-and-mouth disease virus through macropinocytosis

Abstract Foot-and-mouth disease virus (FMDV), a member of the Picornavirus family, poses a significant threat to global animal husbandry. While it is known that macropinocytosis plays a crucial role in the entry of FMDV into cells, the specific cellular proteins that regulate this process and the do...

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Bibliographic Details

Published in:	Veterinary Research
Main Authors:	Xuefei Wang, Hu Dong, Jin’en Wu, Yun Zhang, Shiqi Sun, Huichen Guo
Format:	Article
Language:	English
Published:	BMC 2025-06-01
Subjects:	FMDV CD44 macropinocytosis internalization
Online Access:	https://doi.org/10.1186/s13567-025-01555-3