Serum metabonomics reveal the effectiveness of human placental mesenchymal stem cell therapy for primary sclerosing cholangitis

Abstract Background The metabolic patterns of human placental-derived mesenchymal stem cell (hP-MSC) treatment for primary sclerosing cholangitis (PSC) remain unclear, and therapeutic effects significantly vary due to individual differences. Therefore, it is crucial to investigate the serological re...

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Bibliographic Details

Published in:	Stem Cell Research & Therapy
Main Authors:	Yingduo Yu, Qigu Yao, Deying Chen, Zhehua Zhang, Qiaoling Pan, Jiong Yu, Hongcui Cao, Liang Li, Lanjuan Li
Format:	Article
Language:	English
Published:	BMC 2024-10-01
Subjects:	Mesenchymal stem cell Metabolomics Mdr2−/− mouse Primary sclerosing cholangitis Chemical isotope-labeled liquid chromatography-mass spectrometry Efficacy biomarker
Online Access:	https://doi.org/10.1186/s13287-024-03967-y