The localization, origin, and impact of platelets in the tumor microenvironment are tumor type-dependent

Abstract Background How platelets interact with and influence the tumor microenvironment (TME) remains poorly characterized. Methods We compared the presence and participation of platelets in the TME of two tumors characterized by highly different TME, PyMT AT-3 mammary tumors and B16F1 melanoma. Re...

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發表在:	Journal of Experimental & Clinical Cancer Research
Main Authors:	Ophélie Le Chapelain, Soumaya Jadoui, Angèle Gros, Samir Barbaria, Keltouma Benmeziane, Véronique Ollivier, Sébastien Dupont, Mialitiana Solo Nomenjanahary, Sabrina Mavouna, Jasmina Rogozarski, Marie-Anne Mawhin, Giuseppina Caligiuri, Sandrine Delbosc, Françoise Porteu, Bernhard Nieswandt, Pierre H Mangin, Yacine Boulaftali, Benoit Ho-Tin-Noé
格式:	Article
語言:	英语
出版:	BMC 2024-03-01
主題:	Platelets Solid tumors Tumor microenvironment Vascular integrity Thrombocytopenia
在線閱讀:	https://doi.org/10.1186/s13046-024-03001-2