The role of demethylase AlkB homologs in cancer
The AlkB family (ALKBH1-8 and FTO), a member of the Fe (II)- and α-ketoglutarate-dependent dioxygenase superfamily, has shown the ability to catalyze the demethylation of a variety of substrates, including DNA, RNA, and histones. Methylation is one of the natural organisms’ most prevalent forms of e...
| Published in: | Frontiers in Oncology |
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| Main Authors: | , |
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2023-03-01
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| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2023.1153463/full |