Intravesical instillation-based mTOR-STAT3 dual targeting for bladder cancer treatment

Abstract Background Recent intravesical administration of adenoviral vectors, either as a single injection or in combination with immune checkpoint inhibitors, exemplified by cretostimogene grenadenorepvec and nadofaragene firadenovec, has demonstrated remarkable efficacy in clinical trials for non-...

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Bibliographic Details

Published in:	Journal of Experimental & Clinical Cancer Research
Main Authors:	Dae Hoon Lee, Jung Ki Yoo, Ki Hwan Um, Wootae Ha, Soo Min Lee, Junseong Park, Min Jeong Kye, Jungyo Suh, Jin Woo Choi
Format:	Article
Language:	English
Published:	BMC 2024-06-01
Subjects:	Bladder cancer mTOR STAT3 siRNA Cancer therapy
Online Access:	https://doi.org/10.1186/s13046-024-03088-7