Dual Induction of TREM2 and Tolerance-Related Transcript, Tmem176b, in Amyloid Transgenic Mice: Implications for Vaccine-Based Therapies for Alzheimer's Disease

Vaccine-based autoimmune (anti-amyloid) treatments are currently being examined for their therapeutic potential in Alzheimer's disease. In the present study we examined, in a transgenic model of amyloid pathology, the expression of two molecules previously implicated in decreasing the severity...

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Bibliographic Details

Published in:	ASN Neuro
Main Authors:	Benoit Melchior, Angie E Garcia, Bor-Kai Hsiung, Katherine M Lo, Jonathan M Doose, J Cameron Thrash, Anna K Stalder, Matthias Staufenbiel, Harald Neumann, Monica J Carson
Format:	Article
Language:	English
Published:	Taylor & Francis 2010-06-01
Online Access:	https://doi.org/10.1042/AN20100010