AOC3 accelerates lung metastasis of osteosarcoma by recruiting tumor-associated neutrophils, neutrophil extracellular trap formation and tumor vascularization

Osteosarcoma (OS) has strong invasiveness, early metastasis, high drug resistance, and poor prognosis. At present, OS still lacks reliable biomarkers, which makes early diagnosis of OS more difficult. AOC3 is highly expressed in OS and highly correlated with lung metastasis. qRT-PCR could identify m...

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Bibliographic Details

Published in:	Heliyon
Main Authors:	Luxia Qi, Tian Gao, Chujie Bai, Zhanfei Guo, Linjing Zhou, Xiaodong Yang, Zhengfu Fan, Guifang Zhang
Format:	Article
Language:	English
Published:	Elsevier 2024-09-01
Subjects:	Osteosarcoma AOC3 Neutrophils NETs Angiogenesis
Online Access:	http://www.sciencedirect.com/science/article/pii/S2405844024131015