Effect of Methylation Status of lncRNA-MALAT1 and MicroRNA-146a on Pulmonary Function and Expression Level of COX2 in Patients With Chronic Obstructive Pulmonary Disease

This study aimed to investigate the role of methylation of MALAT1 and miR-146a in the pathogenesis of chronic obstructive pulmonary disease (COPD). COPD patients were grouped according to their methylation status of MALAT1 and miR-146a promoters, and we found that forced vital capacity, volume that...

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Bibliographic Details

Published in:	Frontiers in Cell and Developmental Biology
Main Authors:	Li Sun, Aiqun Xu, Min Li, Xingyuan Xia, Pulin Li, Rui Han, Guanghe Fei, Sijing Zhou, Ran Wang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-09-01
Subjects:	COPD MALAT1 miRNA COX2 methylation
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2021.667624/full