Cryo-EM structure of the potassium-chloride cotransporter KCC4 in lipid nanodiscs

Cation-chloride-cotransporters (CCCs) catalyze transport of Cl- with K+ and/or Na+across cellular membranes. CCCs play roles in cellular volume regulation, neural development and function, audition, regulation of blood pressure, and renal function. CCCs are targets of clinically important drugs incl...

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Bibliographic Details

Published in:	eLife
Main Authors:	Michelle S Reid, David M Kern, Stephen Graf Brohawn
Format:	Article
Language:	English
Published:	eLife Sciences Publications Ltd 2020-04-01
Subjects:	ion transport potassium chloride cotransporter cryo-EM nanodisc
Online Access:	https://elifesciences.org/articles/52505