Predicting effect of anti-PD-1/PD-L1 inhibitors therapy for hepatocellular carcinoma by detecting plasma metabolite based on UHPLC-MS

IntroductionAnti-PD-1/PD-L1 inhibitors therapy has become a promising treatment for hepatocellular carcinoma (HCC), while the therapeutic efficacy varies significantly among effects for individual patients are significant difference. Unfortunately, specific predictive biomarkers indicating the degre...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Botong Liu, Jinyu Shi, Rui Su, Ran Zheng, Fan Xing, Yuan Zhang, Nanya Wang, Huanwen Chen, Shouhua Feng
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-04-01
Subjects:	anti-PD-1/PD-L1 inhibitors therapy hepatocellular carcinoma UHPLC-MS plasma metabolite prognosis
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1370771/full