Nimesulide, a COX-2 inhibitor, sensitizes pancreatic cancer cells to TRAIL-induced apoptosis by promoting DR5 clustering †

Nimesulide is a nonsteroidal anti-inflammatory drug and a COX-2 inhibitor with antitumor and antiproliferative activities that induces apoptosis in oral, esophagus, breast, and pancreatic cancer cells. Despite being removed from the market due to hepatotoxicity, nimesulide is still an important rese...

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書誌詳細

出版年:	Cancer Biology & Therapy
主要な著者:	Nagamani Vunnam, Malaney C. Young, Elly E. Liao, Chih Hung Lo, Evan Huber, MaryJane Been, David D. Thomas, Jonathan N. Sachs
フォーマット:	論文
言語:	英語
出版事項:	Taylor & Francis Group 2023-12-01
主題:	nimesulide cox-2 inhibitors pancreatic cancer cells tumor necrosis factor receptors death receptor 5 tnf-related apoptosis inducing ligand
オンライン･アクセス:	http://dx.doi.org/10.1080/15384047.2023.2176692