Temporal trends in tolvaptan use after revision of national heart failure guidelines in Japan

Abstract Within no definite diuretic protocol for acute heart failure (AHF) patients and its variation in regional clinical guidelines, the latest national guidelines in Japan commends use of tolvaptan in diuretic-resistant patients. This study aimed to examine trends in tolvaptan usage and associat...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Yusuke Yamazaki, Yasuyuki Shiraishi, Shun Kohsaka, Yuji Nagatomo, Keiichi Fukuda, Takashi Kohno, Tsutomu Yoshikawa
Format:	Article
Language:	English
Published:	Nature Portfolio 2021-09-01
Online Access:	https://doi.org/10.1038/s41598-021-98173-8