NKG2D Ligand Shedding in Response to Stress: Role of ADAM10
NKG2D is an activating receptor expressed by NK cells and some subsets of T cells and represents a major recognition receptor for detection and elimination of cancer cells. The ligands of NKG2D are stress-induced self-proteins that can be secreted as soluble molecules by protease-mediated cleavage....
| Published in: | Frontiers in Immunology |
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| Main Authors: | , , , |
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2020-03-01
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| Subjects: | |
| Online Access: | https://www.frontiersin.org/article/10.3389/fimmu.2020.00447/full |