p73α1, an Isoform of the p73 Tumor Suppressor, Modulates Lipid Metabolism and Cancer Cell Growth via Stearoyl-CoA Desaturase-1

Altered lipid metabolism is a hallmark of cancer. p73, a p53 family member, regulates cellular processes and is expressed as multiple isoforms. However, the role of p73 in regulating lipid metabolism is not well-characterized. Previously, we found that loss of p73 exon 12 (<i>E12</i>) le...

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Bibliographic Details

Published in:	Cells
Main Authors:	Zachary Rabow, Kyra Laubach, Xiangmudong Kong, Tong Shen, Shakur Mohibi, Jin Zhang, Oliver Fiehn, Xinbin Chen
Format:	Article
Language:	English
Published:	MDPI AG 2022-08-01
Subjects:	p73 isoforms the p53 family Stearoyl-CoA Desaturase lipid metabolism Kennedy pathway
Online Access:	https://www.mdpi.com/2073-4409/11/16/2516