Transcriptional defects and reprogramming barriers in somatic cell nuclear reprogramming as revealed by single-embryo RNA sequencing

Abstract Background Nuclear reprogramming reinstates totipotency or pluripotency in somatic cells by changing their gene transcription profile. This technology is widely used in medicine, animal husbandry and other industries. However, certain deficiencies severely restrict the applications of this...

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Bibliographic Details
Published in:BMC Genomics
Main Authors: Yong Liu, Fengrui Wu, Ling Zhang, Xiaoqing Wu, Dengkun Li, Jing Xin, Juan Xie, Feng Kong, Wenying Wang, Qiaoqin Wu, Di Zhang, Rong Wang, Shaorong Gao, Wenyong Li
Format: Article
Language:English
Published: BMC 2018-10-01
Subjects:
Transcriptional defect
Reprogramming barrier
SCNT embryo
RNA-seq
Mouse
Online Access:http://link.springer.com/article/10.1186/s12864-018-5091-1

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http://link.springer.com/article/10.1186/s12864-018-5091-1

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