Nuciferine Protects Cochlear Hair Cells from Ferroptosis through Inhibiting NCOA4-Mediated Ferritinophagy

Cisplatin is a widely used antineoplastic drug for treating various types of cancers. However, it can cause severe side effects, such as bilateral and irreversible hearing loss, which significantly impacts quality of life. Ferroptosis, an iron-dependent form of programmed cell death, has been implic...

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Bibliographic Details

Published in:	Antioxidants
Main Authors:	Xian Gao, Huanyu Mao, Liping Zhao, Xiang Li, Yaqi Liao, Wenyan Li, Huawei Li, Yan Chen
Format:	Article
Language:	English
Published:	MDPI AG 2024-06-01
Subjects:	hearing loss cochlear hair cells nuciferine ferroptosis ferritinophagy ototoxicity
Online Access:	https://www.mdpi.com/2076-3921/13/6/714