High-fat diet induces pre-eclampsia through dampening cell-autonomous C3 in trophoblasts

Abstract Hyperlipidemia contributes to low-grade inflammation and abnormal immune response, which is putatively involved in the development of pre-eclampsia (PE). As components of innate immune system, complements play a critical role in regulating inflammation. However, how cell-autonomous compleme...

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Bibliographic Details

Published in:	Communications Biology
Main Authors:	Simeng Zhu, Siyue Chen, Yingzhou Ge, Fangyue Zhou, Kaizhen Su, Congfeng Xu, Yanting Wu, Hefeng Huang
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-06-01
Online Access:	https://doi.org/10.1038/s42003-025-08298-z