Generation of a new DiCre expressing parasite strain for functional characterization of Plasmodium falciparum genes in blood stages

Abstract Conditional regulation is a highly beneficial system for studying the function of essential genes in Plasmodium falciparum and dimerizable Cre recombinase (DiCre) is a recently adapted conditional regulation system suitable for this purpose. In the DiCre system, two inactive fragments of Cr...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Abhisheka Bansal, Manish Sharma, Himashree Choudhury
Format:	Article
Language:	English
Published:	Nature Portfolio 2024-10-01
Subjects:	Plasmodium Dimerizable cre recombinase LoxP CRISPR-Cas9 Rapamycin Conditional regulation
Online Access:	https://doi.org/10.1038/s41598-024-75657-x