The Actin Cytoskeleton Responds to Inflammatory Cues and Alters Macrophage Activation

Much remains to be learned about the molecular mechanisms underlying a class of human disorders called actinopathies. These genetic disorders are characterized by loss-of-function mutations in actin-associated proteins that affect immune cells, leading to human immunopathology. However, much remains...

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Bibliographic Details

Published in:	Cells
Main Authors:	Elsa Ronzier, Alexander J. Laurenson, Rohini Manickam, Sophia Liu, Imelda M. Saintilma, Dillon C. Schrock, John A. Hammer, Jeremy D. Rotty
Format:	Article
Language:	English
Published:	MDPI AG 2022-05-01
Subjects:	actin cytoskeleton Arp2/3 complex myosin-II macrophages iNOS inflammation
Online Access:	https://www.mdpi.com/2073-4409/11/11/1806