Comprehensive profiling of extrachromosomal circular DNAs in colorectal cancer progression

Abstract Colorectal cancer (CRC) development involves a series of molecular events that drive the progression from normal colorectal epithelium to adenoma and eventually to invasive carcinoma. While the involvement of extrachromosomal circular DNAs (ecDNAs) in cancer genome remodeling has been estab...

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Bibliographic Details
Published in:Scientific Reports
Main Authors: Lu Lu, Mingjie Chen, Guicheng Zhang, Yujing Liu, Xiangyuan Xu, Zenghua Jiang, Yangxian Xu, Tao Liu, Fan Yang, Guang Ji, Hanchen Xu
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Subjects:
Circular DNAs
chr8 ecDNA 64950741–114379093
CRC progression
Biomarker
Online Access:https://doi.org/10.1038/s41598-024-70455-x

Internet

https://doi.org/10.1038/s41598-024-70455-x

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