Design, Synthesis, and Antiproliferative Activity of Benzopyran-4-One-Isoxazole Hybrid Compounds

The biological significance of benzopyran-4-ones as cytotoxic agents against multi-drug resistant cancer cell lines and isoxazoles as anti-inflammatory agents in cellular assays prompted us to design and synthesize their hybrid compounds and explore their antiproliferative activity against a panel o...

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Bibliographic Details
Published in:Molecules
Main Authors: Shilpi Gupta, Shang Eun Park, Saghar Mozaffari, Bishoy El-Aarag, Keykavous Parang, Rakesh Kumar Tiwari
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Subjects:
antiproliferative
apoptosis
benzopyranone
chromone
drug discovery
isoxazole
Online Access:https://www.mdpi.com/1420-3049/28/10/4220

Internet

https://www.mdpi.com/1420-3049/28/10/4220

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