ThermOptCobra: Thermodynamically optimal construction and analysis of metabolic networks for reliable phenotype predictions

Summary: Reliable genome-scale metabolic models (GEMs) of metabolic processes are important for understanding cellular behavior. However, the presence of thermodynamically infeasible cycles (TICs) limits their predictive ability. We present ThermOptCOBRA, a comprehensive solution consisting of four...

全面介紹

書目詳細資料
發表在:iScience
Main Authors: Pavan Kumar S, Nirav Pravinbhai Bhatt
格式: Article
語言:英语
出版: Elsevier 2025-08-01
主題:
在線閱讀:http://www.sciencedirect.com/science/article/pii/S2589004225012660