Integrated proteomics analysis and network pharmacology to elucidate the mechanism of Zhilong Huoxue Tongyu Capsule alleviate hypertensive retinopathy in Ang II infusion mice model

BackgroundZhilong Huoxue Tongyu Capsule (ZLHXTY) has been used in clinical treatment of vascular diseases caused by hypertension over 20 years. However, the specific mechanisms by ZLHXTY alleviate hypertensive retinopathy (HR) needs to be further explored.Materials and methodsHR mouse model was esta...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Jiao Wu, Wen Xie, Yucen Xie, Maryam Mazhar, Junguo Duan
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-05-01
Subjects:	ZhiLong HuoXue TongYu Capsule traditional Chinese medicine hypertensive retinopathy NLRP3 inflammasome pyroptosis
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1573693/full