Case Report: Tocilizumab Treatment for VEXAS Syndrome With Relapsing Polychondritis: A Single-Center, 1-Year Longitudinal Observational Study In Japan

Vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic (VEXAS) syndrome is an autoinflammatory disease caused by somatic variants in the UBA1 gene that lead to severe systemic inflammation and myelodysplastic syndrome. Although no standard therapy has been established yet, azacitidine and bone mar...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Yosuke Kunishita, Yohei Kirino, Naomi Tsuchida, Ayaka Maeda, Yuichiro Sato, Kaoru Takase-Minegishi, Ryusuke Yoshimi, Hideaki Nakajima
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-06-01
Subjects:	VEXAS syndrome relapsing polychondritis autoinflammatory diseases tocilizumab (TCZ) 1-year follow-up
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.901063/full