Reducing Brain Edema Using Berotralstat, an Inhibitor of Bradykinin, Repurposed as Treatment Adjunct in Glioblastoma
Glioblastomas synthesize, bear receptors for, and respond to bradykinin, triggering migration and proliferation. Since centrifugal migration into uninvolved surrounding brain tissue occurs early in the course of glioblastoma, this attribute defeats local treatment attempts and is the primary reason...
| Published in: | Neuroglia |
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| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2024-07-01
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| Subjects: | |
| Online Access: | https://www.mdpi.com/2571-6980/5/3/16 |