Comparative in vivo characterization of newly discovered myotropic adeno-associated vectors

Abstract Background Adeno-associated virus (AAV)-based gene therapy is a promising strategy to treat muscle diseases. However, this strategy is currently confronted with challenges, including a lack of transduction efficiency across the entire muscular system and toxicity resulting from off-target t...

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Bibliographic Details
Published in:Skeletal Muscle
Main Authors: Jacqueline Ji, Elise Lefebvre, Jocelyn Laporte
Format: Article
Language:English
Published: BMC 2024-05-01
Subjects:
Adeno-associated virus
AAV
Tissue targeting
Myotropism
Gene therapy
Muscle
Online Access:https://doi.org/10.1186/s13395-024-00341-7

Internet

https://doi.org/10.1186/s13395-024-00341-7

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