Rapid and Reproducible Differentiation of Hematopoietic and T Cell Progenitors From Pluripotent Stem Cells

Cell therapy using T cells has revolutionized medical care in recent years but limitations are associated with the difficulty of genome editing of the cells, the production of a sufficient number of cells and standardization of the product. Human pluripotent stem cells (hPSCs) can self-renew and dif...

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Bibliographic Details

Published in:	Frontiers in Cell and Developmental Biology
Main Authors:	Léa Flippe, Anne Gaignerie, Céline Sérazin, Olivier Baron, Xavier Saulquin, Maria Themeli, Carole Guillonneau, Laurent David
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2020-10-01
Subjects:	hiPSC hESC hematopoietic progenitor T-cell progenitor hematopoietic differentiation
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2020.577464/full