Cryo-EM reveals distinct conformations of E. coli ATP synthase on exposure to ATP

ATP synthase produces the majority of cellular energy in most cells. We have previously reported cryo-EM maps of autoinhibited E. coli ATP synthase imaged without addition of nucleotide (Sobti et al. 2016), indicating that the subunit ε engages the α, β and γ subunits to lock the enzyme and prevent...

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Bibliographic Details

Published in:	eLife
Main Authors:	Meghna Sobti, Robert Ishmukhametov, James C Bouwer, Anita Ayer, Cacang Suarna, Nicola J Smith, Mary Christie, Roland Stocker, Thomas M Duncan, Alastair G Stewart
Format:	Article
Language:	English
Published:	eLife Sciences Publications Ltd 2019-03-01
Subjects:	ATP synthase cryo-EM inhibition
Online Access:	https://elifesciences.org/articles/43864