High levels of TDO2 in relation to pro-inflammatory cytokines in synovium and synovial fluid of patients with osteoarthritis

Abstract Background Tryptophan 2,3-dioxygenase (TDO2) is the primary enzyme that catabolizes tryptophan to kynurenine. Numerous studies have suggested that TDO2 is involved in inflammation-related diseases. However, its role in osteoarthritis (OA) has not yet been investigated. The aim of the presen...

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Bibliographic Details

Published in:	BMC Musculoskeletal Disorders
Main Authors:	Genxiang Rong, Tao Zhang, Yayun Xu, Zhenyu Zhang, Binjie Gui, Kongzu Hu, Jinling Zhang, Zhi Tang, Cailiang Shen
Format:	Article
Language:	English
Published:	BMC 2022-06-01
Subjects:	Osteoarthritis Tryptophan 2,3-dioxygenase Synovial fluid Synovium Pro-inflammatory cytokines
Online Access:	https://doi.org/10.1186/s12891-022-05567-4