Persistent lymphocytopenia in convalescent patients with COVID-19: dysregulated B cell, CD4+ T cell, and treg compartments in 7–12% of moderate-severe cases

BackgroundLong COVID manifests with heterogeneous clinical outcomes, potentially linked to immune dysfunction. However, the recovery of immune-cell subsets during convalescence remains incompletely understood.MethodsIn this longitudinal cohort, 279 unvaccinated patients with confirmed SARS-CoV-2 inf...

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Bibliographic Details

Published in:	Frontiers in Cellular and Infection Microbiology
Main Authors:	Hui An, Tongtong Yu, Anlan Wang, Hao Hu, Chen Zhang, Yongyu Wang, Ming Li
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-10-01
Subjects:	COVID-19 convalescent patients persistent lymphocytopenia B cells T cells regulatory T cells
Online Access:	https://www.frontiersin.org/articles/10.3389/fcimb.2025.1693743/full