Desensitization Strategies for Donor-Specific Antibodies in HLA-Mismatched Stem Cell Transplantation Recipients: What We Know and What We Do Not Know

Abstract In human leukocyte antigen (HLA)-mismatched allogeneic stem cell transplantation settings, donor-specific anti-HLA antibodies (DSAs) can independently lead to graft failure, including both primary graft rejection and primary poor graft function. Although several strategies, such as plasma e...

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Bibliographic Details

Published in:	Oncology and Therapy
Main Authors:	Yang Zhou, Yu-Lun Chen, Xi-Yi Huang, Ying-Jun Chang
Format:	Article
Language:	English
Published:	Adis, Springer Healthcare 2024-06-01
Subjects:	Allogeneic stem cell transplantation Donor-specific antibody Graft failure Desensitization
Online Access:	https://doi.org/10.1007/s40487-024-00283-6