Luminal-applied flagellin is internalized by polarized intestinal epithelial cells and elicits immune responses via the TLR5 dependent mechanism.

Bacteria release flagellin that elicits innate responses via Toll-like receptor 5 (TLR5). Here, we investigated the fate of apically administrated full length flagellin from virulent and avirulent bacteria, along with truncated recombinant flagellin proteins in intestinal epithelial cells and cellul...

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Bibliographic Details

Published in:	PLoS ONE
Main Authors:	Tonyia Eaves-Pyles, Heng-Fu Bu, Xiao-di Tan, Yingzi Cong, Jignesh Patel, Robert A Davey, Jane E Strasser
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2011-01-01
Online Access:	http://europepmc.org/articles/PMC3174220?pdf=render