A Non-Canonical Role for the Glycosyltransferase Enzyme UGT2B17 as a Novel Constituent of the B Cell Receptor Signalosome

In chronic lymphocytic leukemia (CLL), an elevated glycosyltransferase UGT2B17 expression (UGT2B17<sup>HI</sup>) identifies a subgroup of patients with shorter survival and poor drug response. We uncovered a mechanism, possibly independent of its enzymatic function, characterized by an e...

書目詳細資料
發表在:	Cells
Main Authors:	Antoine Wagner, Michèle Rouleau, Lyne Villeneuve, Trang Le, Cheryl Peltier, Éric P. Allain, Caroline Beaudoin, Sophie Tremblay, Fréderic Courtier, Flora Nguyen Van Long, Isabelle Laverdière, Éric Lévesque, Versha Banerji, Katrina Vanura, Chantal Guillemette
格式:	Article
語言:	英语
出版:	MDPI AG 2023-05-01
主題:	glycosyltransferase UGT2B17 CLL B cell receptor BTK ZAP70
在線閱讀:	https://www.mdpi.com/2073-4409/12/9/1295

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