Parathyroid hormone (1–34) can reverse the negative effect of valproic acid on the osseointegration of titanium rods in ovariectomized rats

Objective: The present work was aimed to evaluate the effect of valproic acid (VPA),Parathyroid hormone (1–34) (PTH)+VPA on Ti rods osseointegration in ovariectomized rats and further investigation of the possible mechanism. Methods: The MC3T3-E1 cells were co-cultured with VPA,PTH ​+ ​VPA and induc...

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Bibliographic Details
Published in:Journal of Orthopaedic Translation
Main Authors: Zhou-Shan Tao, Wan-Shu Zhou, Hong-Guang Xu, Min Yang
Format: Article
Language:English
Published: Elsevier 2021-03-01
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214031X20301182