Alcohol Metabolizing Enzymes, Microsomal Ethanol Oxidizing System, Cytochrome P450 2E1, Catalase, and Aldehyde Dehydrogenase in Alcohol-Associated Liver Disease

Once ingested, most of the alcohol is metabolized in the liver by alcohol dehydrogenase to acetaldehyde. Two additional pathways of acetaldehyde generation are by microsomal ethanol oxidizing system (cytochrome P450 2E1) and catalase<b>. </b>Acetaldehyde can form adducts which can interf...

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Bibliographic Details

Published in:	Biomedicines
Main Authors:	Yanchao Jiang, Ting Zhang, Praveen Kusumanchi, Sen Han, Zhihong Yang, Suthat Liangpunsakul
Format:	Article
Language:	English
Published:	MDPI AG 2020-03-01
Subjects:	alcohol metabolizing enzyme cytochrome p450 2e1 and alcohol-associated liver disease
Online Access:	https://www.mdpi.com/2227-9059/8/3/50