Research on the process and molecular mechanism of inhibiting serous ovarian cancer by PRTN3 and its inhibitor Sivelestat

Abstract Background Serous ovarian cancer (SOC) is one of the most important diseases affecting women’s health in the world. It is highly occult and often detected in late stage due to the lack of specific molecular markers. Methods Whole exon sequencing was performed on 38 serous ovarian cancer sam...

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Bibliographic Details

Published in:	Journal of Ovarian Research
Main Authors:	Changtao Zheng, Luzhu Chen, Xiaotian Lv, Yaoyao He, Xiangyun Hu, Ying Ding, Sheng Wang, Peng Wei, Tao Zhang, Huainian Zhang, Xiaoting Zhang, Yongli Zhang
Format:	Article
Language:	English
Published:	BMC 2025-09-01
Subjects:	Serous ovarian cancer Whole-exome sequencing PRTN3 Sivelestat Therapeutic target Molecular marker
Online Access:	https://doi.org/10.1186/s13048-025-01808-x