Single-cell transcriptome analysis of medaka lymphocytes reveals absence of fully mature T cells in the thymus and the T-lineage commitment in the kidney

The cellular and molecular mechanisms underlying lymphocyte development are diverse among teleost species. Although recent scRNA-seq analyses of zebrafish hematopoietic cells have advanced our understanding of teleost hematopoiesis, comparative studies using another genetic model, medaka, which is e...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Hiyori Sakaguchi, Masaru Matsuda, Norimasa Iwanami
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-01-01
Subjects:	medaka immune system lymphopoiesis scRNA-seq rag1
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1517467/full