A Review of Quinazoline-Based EGFR/VEGFR-2 Dual Inhibitors as Potent Anticancer Agents: Structure-Activity Relationship and Docking Studies

The epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase (RTK) that initiates various signaling pathways resulting in processes such as gene expression, proliferation, angiogenesis, and inhibition of apoptosis. Dysregulation of EGFR signaling causes tumor development and metastasis....

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Bibliographic Details

Published in:	Pharmaceutical Sciences
Main Authors:	Fatemeh Yousefbeyk, Saeed Ghasemi
Format:	Article
Language:	English
Published:	Tabriz University of Medical Sciences 2025-01-01
Subjects:	dual inhibitors egfr kinase quinazolines structure-activity relationship vegfr-2
Online Access:	https://ps.tbzmed.ac.ir/PDF/ps-31-43.pdf