Structure and function of the metagenomic plastic-degrading polyester hydrolase PHL7 bound to its product

The authors describe the cocrystal structure of the highly efficient polyethylene terephthalate-degrading hydrolase PHL7 with its product terephthalic acid and elucidate the role of residues in subsites I and II for its thermal stability and of residue L210 for its high activity.

Bibliographic Details

Published in:	Nature Communications
Main Authors:	P. Konstantin Richter, Paula Blázquez-Sánchez, Ziyue Zhao, Felipe Engelberger, Christian Wiebeler, Georg Künze, Ronny Frank, Dana Krinke, Emanuele Frezzotti, Yuliia Lihanova, Patricia Falkenstein, Jörg Matysik, Wolfgang Zimmermann, Norbert Sträter, Christian Sonnendecker
Format:	Article
Language:	English
Published:	Nature Portfolio 2023-04-01
Online Access:	https://doi.org/10.1038/s41467-023-37415-x