Coordinated regulation of chromatin modifiers reflects organised epigenetic programming in mouse oocytes

Abstract Background Epigenetic modifications provide mechanisms for influencing gene expression, regulating cell differentiation and maintaining long-term memory of cellular identity and function. As oocytes transmit epigenetic information to offspring, correct establishment of the oocyte epigenome...

Full description

Bibliographic Details

Published in:	Epigenetics & Chromatin
Main Authors:	Chloe A. Edwards-Lee, Ellen G. Jarred, Patrick S. Western
Format:	Article
Language:	English
Published:	BMC 2025-04-01
Subjects:	Epigenetic programming Maternal germline Oocytes Histone modifications DNA methylation PRC2
Online Access:	https://doi.org/10.1186/s13072-025-00583-9