Frizzled1 and Frizzled2 are not redundant for competitive survival under low-Wingless levels in the developing Drosophila wing epithelium

In the Drosophila wing epithelium, canonical Wnt signalling is activated by the gradient of secreted Wingless protein (Wnt1 homolog), which interacts redundantly with the Frizzled1 and Frizzled2 receptors. While sharing overlapping functions, these receptors also have distinct non-canonical roles an...

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Bibliographic Details

Published in:	Open Biology
Main Authors:	Swapnil Hingole, Kritika Verma, Varun Chaudhary
Format:	Article
Language:	English
Published:	The Royal Society 2025-01-01
Subjects:	Wingless Frizzled Frizzled2 canonical Wnt signalling cell survival cell competition
Online Access:	https://royalsocietypublishing.org/doi/10.1098/rsob.240381