TMAO, a seafood-derived molecule, produces diuresis and reduces mortality in heart failure rats
Trimethylamine-oxide (TMAO) is present in seafood which is considered to be beneficial for health. Deep-water animals accumulate TMAO to protect proteins, such as lactate dehydrogenase (LDH), against hydrostatic pressure stress (HPS). We hypothesized that TMAO exerts beneficial effects on the circul...
| 發表在: | eLife |
|---|---|
| Main Authors: | Marta Gawrys-Kopczynska, Marek Konop, Klaudia Maksymiuk, Katarzyna Kraszewska, Ladislav Derzsi, Krzysztof Sozanski, Robert Holyst, Marta Pilz, Emilia Samborowska, Leszek Dobrowolski, Kinga Jaworska, Izabella Mogilnicka, Marcin Ufnal |
| 格式: | Article |
| 語言: | 英语 |
| 出版: |
eLife Sciences Publications Ltd
2020-06-01
|
| 主題: | |
| 在線閱讀: | https://elifesciences.org/articles/57028 |
相似書籍
Spontaneously hypertensive rats exhibit increased liver flavin monooxygenase expression and elevated plasma TMAO levels compared to normotensive and Ang II-dependent hypertensive rats
由: Marta Gawryś-Kopczyńska, et al.
出版: (2024-04-01)
由: Marta Gawryś-Kopczyńska, et al.
出版: (2024-04-01)
Trimethylamine-N-oxide (TMAO) versus echocardiographic, biochemical and histopathological indices of heart failure in patients with severe aortic stenosis: Rationale and design of the prospective, observational TASTE study
由: Aleksandra Gąsecka, et al.
出版: (2022-07-01)
由: Aleksandra Gąsecka, et al.
出版: (2022-07-01)
TMAO metaorganismal pathway and chronic inflammatory diseases
由: Zeneng Wang, et al.
出版: (2025-06-01)
由: Zeneng Wang, et al.
出版: (2025-06-01)
Mice, rats, and guinea pigs differ in FMOs expression and tissue concentration of TMAO, a gut bacteria-derived biomarker of cardiovascular and metabolic diseases
由: Klaudia M. Maksymiuk, et al.
出版: (2024-01-01)
由: Klaudia M. Maksymiuk, et al.
出版: (2024-01-01)
From heart failure and kidney dysfunction to cardiorenal syndrome: TMAO may be a bridge
由: Jialun Zhang, et al.
出版: (2023-11-01)
由: Jialun Zhang, et al.
出版: (2023-11-01)
Screening freshness of seafood by measuring trimethylamine (TMA) levels using helium-plasma ionization mass spectrometry (HePI-MS)
由: Isuru S. Herath, et al.
出版: (2019-11-01)
由: Isuru S. Herath, et al.
出版: (2019-11-01)
Prevalence of Antibiotic-Resistant Seafood-Borne Pathogens in Retail Seafood Sold in Malaysia: A Systematic Review and Meta-Analysis
由: Omowale A. Odeyemi, et al.
出版: (2023-04-01)
由: Omowale A. Odeyemi, et al.
出版: (2023-04-01)
A Critical Appraisal of Global Testing Protocols for Zoonotic Parasites in Imported Seafood Applied to Seafood Safety in Australia
由: Michelle Williams, et al.
出版: (2020-04-01)
由: Michelle Williams, et al.
出版: (2020-04-01)
Seafood traceability system: A comprehensive assessment of seafood establishments in the Sultanate of Oman
由: Ward Al Muna Al Mandhari, et al.
出版: (2025-11-01)
由: Ward Al Muna Al Mandhari, et al.
出版: (2025-11-01)
Cellular Agriculture for Production of Cell-Based Seafood
由: Razieh Farzad
出版: (2021-09-01)
由: Razieh Farzad
出版: (2021-09-01)
Dataset on cardiac structural and functional parameters in TMAO-challenged mouse
由: Yingyu Wang, et al.
出版: (2024-06-01)
由: Yingyu Wang, et al.
出版: (2024-06-01)
Association of TMAO levels with indicators of ulcerative colitis activity
由: Yelena Laryushina, et al.
出版: (2025-10-01)
由: Yelena Laryushina, et al.
出版: (2025-10-01)
Simultaneous Measurement of Urinary Trimethylamine (TMA) and Trimethylamine <i>N</i>-Oxide (TMAO) by Liquid Chromatography–Mass Spectrometry
由: Xun Jia, et al.
出版: (2020-04-01)
由: Xun Jia, et al.
出版: (2020-04-01)
IoT Platform for Seafood Farmers and Consumers
由: Bjørn Jæger, et al.
出版: (2020-07-01)
由: Bjørn Jæger, et al.
出版: (2020-07-01)
Factors influencing seafood sales in US retail markets
由: Lianqun Sun, et al.
出版: (2025-02-01)
由: Lianqun Sun, et al.
出版: (2025-02-01)
Shopping for Health: Seafood
由: Michelle Brown, et al.
出版: (2015-02-01)
由: Michelle Brown, et al.
出版: (2015-02-01)
Structure and evolution of the global seafood trade network
由: Jessica A Gephart, et al.
出版: (2015-01-01)
由: Jessica A Gephart, et al.
出版: (2015-01-01)
Seafood Safety and Quality: The Consumer’s Role
由: Doris T. Hicks
出版: (2016-10-01)
由: Doris T. Hicks
出版: (2016-10-01)
Trimethylamine N-Oxide (TMAO) Plasma Levels in Patients with Different Stages of Chronic Kidney Disease
由: Marcia Ribeiro, et al.
出版: (2024-12-01)
由: Marcia Ribeiro, et al.
出版: (2024-12-01)
TMAO Induces Vascular Endothelial Cells Pyroptosis Through TET2-CYTB-ROS Pathway
由: Xia L, et al.
出版: (2025-07-01)
由: Xia L, et al.
出版: (2025-07-01)
TMAO and the gut microbiome: implications for the CVD-CKD-IBD axis
由: Si Hyoung Kim, et al.
出版: (2025-12-01)
由: Si Hyoung Kim, et al.
出版: (2025-12-01)
Effect of three oral pathogens on the TMA-TMAO metabolic pathway
由: Xixuan Wang, et al.
出版: (2024-05-01)
由: Xixuan Wang, et al.
出版: (2024-05-01)
Rhode Island Branding Program for Local Seafood
由: Nicole Richard, et al.
出版: (2020-01-01)
由: Nicole Richard, et al.
出版: (2020-01-01)
Trimethylamine-N-oxide (TMAO) increased aquaporin-2 expression in spontaneously hypertensive rats
由: Min Liu, et al.
出版: (2019-05-01)
由: Min Liu, et al.
出版: (2019-05-01)
Public awareness of seafood mislabeling
由: Savannah J. Ryburn, et al.
出版: (2022-06-01)
由: Savannah J. Ryburn, et al.
出版: (2022-06-01)
Trimethylamine-N-Oxide (TMAO)-Induced Impairment of Cardiomyocyte Function and the Protective Role of Urolithin B-Glucuronide
由: Monia Savi, et al.
出版: (2018-03-01)
由: Monia Savi, et al.
出版: (2018-03-01)
Transcatheter aortic valve implantation reduces plasma concentrations of TMAO and indoxyl sulfate: A prospective, multicenter cohort study
由: Aleksandra Gąsecka, et al.
出版: (2025-04-01)
由: Aleksandra Gąsecka, et al.
出版: (2025-04-01)
Thyme: A natural preservative for seafood
由: Saman Yousefi
出版: (2022-03-01)
由: Saman Yousefi
出版: (2022-03-01)
Global adoption of aquaculture to supply seafood
由: G D Stentiford, et al.
出版: (2022-01-01)
由: G D Stentiford, et al.
出版: (2022-01-01)
Circulating TMAO, the gut microbiome and cardiometabolic disease risk: an exploration in key precursor disorders
由: Saba Naghipour, et al.
出版: (2024-06-01)
由: Saba Naghipour, et al.
出版: (2024-06-01)
Investigating the Consumption Patterns of Japanese Seafood during the COVID-19 Pandemic
由: Kentaka Aruga, et al.
出版: (2024-05-01)
由: Kentaka Aruga, et al.
出版: (2024-05-01)
DNA Barcoding Revealed Mislabeling of Imported Seafood Products in Thailand
由: Deep Nithun Senathipathi, et al.
出版: (2024-06-01)
由: Deep Nithun Senathipathi, et al.
出版: (2024-06-01)
To Eat or Not to Eat?—Food Safety Aspects of Essential Metals in Seafood
由: József Lehel, et al.
出版: (2023-11-01)
由: József Lehel, et al.
出版: (2023-11-01)
Changes in Marine Seafood Consumption in Tokyo, Japan
由: Tatiana Maria Cecy Gadda, et al.
出版: (2012-12-01)
由: Tatiana Maria Cecy Gadda, et al.
出版: (2012-12-01)
Decoding TMAO in the Gut-Organ Axis: From Biomarkers and Cell Death Mechanisms to Therapeutic Horizons
由: Liu J, et al.
出版: (2025-04-01)
由: Liu J, et al.
出版: (2025-04-01)
Sex-specific differences in trimethylamine N-oxide (TMAO) concentrations before and after cardiac rehabilitation in acute myocardial infarction patients
由: Andreas Baranyi, et al.
出版: (2022-01-01)
由: Andreas Baranyi, et al.
出版: (2022-01-01)
Atherosclerotic patients with diabetes mellitus may break through the threshold of healthy TMAO levels formed by long-term statins therapy
由: Hao Liang, et al.
出版: (2023-02-01)
由: Hao Liang, et al.
出版: (2023-02-01)
The association of plasma TMAO and body composition with the occurrence of PEW in maintenance hemodialysis patients
由: Xinran Wang, et al.
出版: (2025-12-01)
由: Xinran Wang, et al.
出版: (2025-12-01)
TMAO and diabetes: from the gut feeling to the heart of the problem
由: Kinga Jaworska, et al.
出版: (2025-05-01)
由: Kinga Jaworska, et al.
出版: (2025-05-01)
The Influence of Sustainability on Identities and Seafood Consumption: Implications for Food Systems Education for Generation Z
由: Kristin E. Gibson, et al.
出版: (2023-05-01)
由: Kristin E. Gibson, et al.
出版: (2023-05-01)
相似書籍
-
Spontaneously hypertensive rats exhibit increased liver flavin monooxygenase expression and elevated plasma TMAO levels compared to normotensive and Ang II-dependent hypertensive rats
由: Marta Gawryś-Kopczyńska, et al.
出版: (2024-04-01) -
Trimethylamine-N-oxide (TMAO) versus echocardiographic, biochemical and histopathological indices of heart failure in patients with severe aortic stenosis: Rationale and design of the prospective, observational TASTE study
由: Aleksandra Gąsecka, et al.
出版: (2022-07-01) -
TMAO metaorganismal pathway and chronic inflammatory diseases
由: Zeneng Wang, et al.
出版: (2025-06-01) -
Mice, rats, and guinea pigs differ in FMOs expression and tissue concentration of TMAO, a gut bacteria-derived biomarker of cardiovascular and metabolic diseases
由: Klaudia M. Maksymiuk, et al.
出版: (2024-01-01) -
From heart failure and kidney dysfunction to cardiorenal syndrome: TMAO may be a bridge
由: Jialun Zhang, et al.
出版: (2023-11-01)
