The Hemagglutinin of Bat-Associated Influenza Viruses Is Activated by TMPRSS2 for pH-Dependent Entry into Bat but Not Human Cells.

New World bats have recently been discovered to harbor influenza A virus (FLUAV)-related viruses, termed bat-associated influenza A-like viruses (batFLUAV). The internal proteins of batFLUAV are functional in mammalian cells. In contrast, no biological functionality could be demonstrated for the sur...

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Bibliographic Details
Published in:PLoS ONE
Main Authors: Markus Hoffmann, Nadine Krüger, Pawel Zmora, Florian Wrensch, Georg Herrler, Stefan Pöhlmann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Online Access:http://europepmc.org/articles/PMC4814062?pdf=render