Myosin-independent stiffness sensing by fibroblasts is regulated by the viscoelasticity of flowing actin

Abstract The stiffness of the extracellular matrix induces differential tension within integrin-based adhesions, triggering differential mechanoresponses. However, it has been unclear if the stiffness-dependent differential tension is induced solely by myosin activity. Here, we report that in the ab...

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Bibliographic Details

Published in:	Communications Materials
Main Authors:	Nikhil Mittal, Etienne B. Michels, Andrew E. Massey, Yunxiu Qiu, Shaina P. Royer-Weeden, Bryan R. Smith, Alexander X. Cartagena-Rivera, Sangyoon J. Han
Format:	Article
Language:	English
Published:	Nature Portfolio 2024-01-01
Online Access:	https://doi.org/10.1038/s43246-024-00444-0