Identification of the binding site for plasminogen kringle 5 in the α-chain of fibrin(ogen) D-fragment

The interaction of the fifth kringle of Glu-plasminogen with fibrin triggers activation and initiation of fibrinolysis, yet the site on fibrin that binds kringle 5 remains unknown. The aim of our work was to determine an amino acid sequence in the D-fragment of fibrin(ogen) molecule, which is compl...

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Bibliographic Details

Published in:	The Ukrainian Biochemical Journal
Main Authors:	L. G. Kapustianenko, T. V. Grinenko, A. V. Rebriev, O. I. Yusova, A. A. Tykhomyrov
Format:	Article
Language:	English
Published:	National Academy of Sciences of Ukraine, Palladin Institute of Biochemistry 2020-06-01
Subjects:	binding site fibrinogen fibrinolysis kringle 5 plasminogen α-chain of fibrin d-fragment
Online Access:	http://ukrbiochemjournal.org/wp-content/uploads/2020/08/Kapustianenko_3_20.pdf