A Smooth Muscle Cell-Based Ferroptosis Model to Evaluate Iron-Chelating Molecules for Cardiovascular Disease Treatment

Dysregulation of iron homeostasis causes iron-mediated cell death, recently described as ferroptosis. Ferroptosis is reported in many chronic diseases, such as hepatic cancer, renal, and cardiovascular diseases (heart failure, atherosclerosis). However, there is a notable scarcity of research studie...

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Bibliographic Details

Published in:	Current Issues in Molecular Biology
Main Authors:	Sarah El Hajj, Laetitia Canabady-Rochelle, Isabelle Fries-Raeth, Caroline Gaucher
Format:	Article
Language:	English
Published:	MDPI AG 2024-02-01
Subjects:	ferroptosis human aortic smooth muscle cells intracellular GSH lipid peroxidation iron chelation
Online Access:	https://www.mdpi.com/1467-3045/46/2/86