Comparison of Piperacillin and Tazobactam Pharmacokinetics in Critically Ill Patients with Trauma or with Burn

Critical illness caused by burn and sepsis is associated with pathophysiologic changes that may result in the alteration of pharmacokinetics (PK) of antibiotics. However, it is unclear if one mechanism of critical illness alters PK more significantly than another. We developed a population PK model...

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Bibliographic Details
Published in:Antibiotics
Main Authors: Daniel J. Selig, Kevin S. Akers, Kevin K. Chung, Adrian T. Kress, Jeffrey R. Livezey, Elaine D. Por, Kaitlin A. Pruskowski, Jesse P. DeLuca
Format: Article
Language:English
Published: MDPI AG 2022-05-01
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Online Access:https://www.mdpi.com/2079-6382/11/5/618