Multi-omics profiling of DNA methylation and gene expression alterations in human cocaine use disorder

Abstract Structural and functional changes of the brain are assumed to contribute to excessive cocaine intake, craving, and relapse in cocaine use disorder (CUD). Epigenetic and transcriptional changes were hypothesized as a molecular basis for CUD-associated brain alterations. Here we performed a m...

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Bibliographic Details

Published in:	Translational Psychiatry
Main Authors:	Eric Zillich, Hanna Belschner, Diana Avetyan, Diego Andrade-Brito, José Jaime Martínez-Magaña, Josef Frank, Naguib Mechawar, Gustavo Turecki, Judit Cabana-Domínguez, Noèlia Fernàndez-Castillo, Bru Cormand, Janitza L. Montalvo-Ortiz, Markus M. Nöthen, Anita C. Hansson, Marcella Rietschel, Rainer Spanagel, Stephanie H. Witt, Lea Zillich
Format:	Article
Language:	English
Published:	Nature Publishing Group 2024-10-01
Online Access:	https://doi.org/10.1038/s41398-024-03139-9